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This IgG really should neutralize the more frequently encountered HAMA.[ninety] Techniques the laboratory might take To guage this risk consist of employing a bigger dilution on the sample having a reagent that contains the non-immune mouse IgG or carrying out the Evaluation with a differently configured assay, preferably one using distinct species of reagent antibodies.[91]
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Troponin bound to heparin results in decreased measured troponin plasma focus in comparison with serum.[seventy six] Other sources of interference that may have an effect on the assay detection process and induce Bogus-adverse troponin values contain ascorbic acid in immunoenzymometric assays using alkaline phosphatase, biotin in assays employing a biotinylated antibody, streptokinase in the existence of streptavidin, and large titers of antibodies to ruthenium or streptavidin in cTnT assays.
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